Lexogen GmbH 10. Februar 2014

Discovery and quantification with SQUARETM mRNA-Seq [PDF]

The majority of RNA-seq library preparation protocols quantify the expression of genes without taking into account the numerous transcript variants which contribute to this overall expression. SQUARE mRNA-seq uses a selective matrix to separate transcript variants and to enable the assembly and quantification of individual transcripts. The protocol is highly specific for full-length, polyadenylated mRNA, and transcript hypotheses are supported by directional transcription start and polyadenylation site tagging.

Lexogen is an ambitious biotech start-up with unique proprietary expression profiling technologies that enable detailed profiling of the... [mehr]