UNLOCK PICHIA - PRODUCTIVITY THROUGH DIVERSITY

You need stable, robust and scalable processes for commercial manufacturing?

Are you looking for a process yielding consistent product quality?

Are you seeking to acquire process knowledge?

Pichia processes at VTU show extraordinarily high space-time yields and typical product concentrations of 10 - 20 g/l at raw product purities of 80 - 90 % in culture supernatant before downstream processing.

VTU Technology offers straightforward bioprocess development and optimization services. This capability is essential for the elucidation of key process parameters (considering potential scale-up constraints) and for achieving process productivity, quality and robustness levels that will support commercial production of recombinant proteins.

Protein production processes developed in VTU's labs have been shown to be robust and scalable.

To date, several VTU customers have licensed and successfully scaled-up VTU's Pichia processes for the manufacture of recombinant proteins to volumes ranging from several hundred to more than 10,000 l.

Comprehensive documentation and professional support guarantee sound technology transfer of the optimized fermentation process to your production site and straightforward implementation in large-scale production facilities.

Key benefits

Boosted space time yields through optimized VTU cultivation protocols

Reduced manufacturing costs

Scalable, robust, transferable and cmc-ready manufacturing system

Short time lines and high flexibility

Technology

Established platform processes and extensive know-how and experience serve as a basis for successful optimization

State of the art bioreactors equipped with comprehensive online analytics

Design of experiment software tools for efficient parameter scouting and full DoE process development